Laboratory assays reveal diverse phenotypes among microfilariae of Dirofilaria immitis isolates with known macrocyclic lactone susceptibility status
نویسندگان
چکیده
منابع مشابه
Development of an in vitro bioassay for measuring susceptibility to macrocyclic lactone anthelmintics in Dirofilaria immitis☆
For more than 20 years, anthelmintics of the macrocyclic lactone (ML) drug class have been widely and effectively used as preventives against the canine heartworm, Dirofilaria immitis. However, in recent years an increased number of lack of efficacy (LOE) cases are being reported, in which dogs develop mature heartworm infections despite receiving monthly prophylactic doses of ML drugs. While t...
متن کاملPeriodicity of "Dirofilaria immitis" microfilariae in canine and murine hosts
Nutzungsbedingungen Die ETH-Bibliothek ist Anbieterin der digitalisierten Zeitschriften. Sie besitzt keine Urheberrechte an den Inhalten der Zeitschriften. Die Rechte liegen in der Regel bei den Herausgebern. Die auf der Plattform e-periodica veröffentlichten Dokumente stehen für nicht-kommerzielle Zwecke in Lehre und Forschung sowie für die private Nutzung frei zur Verfügung. Einzelne Dateien ...
متن کاملPeriodicity of Dirofilaria immitis microfilariae in canine and murine hosts.
Microfilariae of Dirofilaria immitis were recovered from an experimentally infected dog and inoculated intravenously into adult female BALB/c mice. Each mouse received 1 X 10(5) microfilariae. In one experiment mice were sublethally irradiated with gamma radiation 24 h prior to microfilarial inoculation; microfilariae were counted at 11.00 and 23.00 h 7, 14, 21, 28, 35 and 42 days after inocula...
متن کاملPeriodicity exhibited by Dirofilaria immitis microfilariae identified in dogs of Korea.
Microfilarial periodicity of Dirofilaria immitis (the dog heartworm) was determined at two hr intervals for 72 consecutive hrs in 10 naturally infected war dogs, 3-9 years old, in Korea to facilitate harvest of the microfilariae for possible use in laboratory works and to elucidate further the periodicity of the microfilaria depending on geographic location. Although the periodicity had been ob...
متن کاملFeline Dirofilaria immitis infection
AffectedAnimals: Dogs and cats. Overall, cats are infected by heartworms much less commonly, even in areas in which heavily infected dogs are present. Male cats tend to be infected more commonly and have a larger worm burden than female cats, mostly because male cats spend more time roaming outside and have less resistance to infection than female cats. Cats that spend significant amounts of ti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2020
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0237150